Byline: Howard Hughes Medical Institute
CHEVY CHASE, Md., Nov. 28 (AScribe Newswire) -- Exploiting biology's own chemical toolbox, researchers have developed a new technique that will allow them to modify specific sequences within a DNA molecule. The approach will not only help reveal the impact of biochemical alterations to DNA, but could have far-reaching implications for DNA-based medical diagnosis and nanobiotechnology.
Combining chemistry with biotechnology, Saulius Klimasauskas, a Howard Hughes Medical Institute (HHMI) international research scholar at the Institute of Biotechnology in Vilnius, Lithuania, and chemists at the Institute of Organic Chemistry in Aachen, Germany, have harnessed a group of essential enzymes to add various chemical groups to DNA, thereby altering its function. The work was published in an early online publication on November 27, 2005 in Nature …
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